John Watson

MEDICAL 8 / 8 / 6 male
 If with Sherlock Holmes, you may discard your hand at start of turn.  ENGINEER  Physics

Madam Pulaski

CIVILIAN 7 / 7 / 4 female
 Unique missions seeded by both players are worth +10 points if you complete them.  MEDICAL

Professor Moriarty

CIVILIAN 5 / 12 / 5 male  
 SCIENCE  Leadership  Computer Skill
 Treachery  Once each turn, you may place an additional personnel under Holoprogram: 221B Baker Street.

Regina Barthalomew

V.I.P. 7 / 5 / 4 female  
 If with Professor Moriarty, copies of personnel under Holoprogram: 221B Baker Street may report for free.

Sherlock Holmes

CIVILIAN 8 / 12 / 12 male
 Biology  Physics  Music
 Computer Skill  At start of your turn, you may draw cards (without downloading) until your hand is equal to opponent's.

Personnel with 'Sherlock Holmes' in lore are referenced by:  Holoprogram: 221B Baker Street